Graminex - Products containing Flower Pollen Extract

Graminex is the exclusive manufacturer of Graminex ™ Flower Pollen Extract in the United States. The Corporate headquarters are located in Graminex Manufacturing Facility in Deshler, Ohio

Graminex Manufacturing Facility in Deshler, Ohio

Saginaw, Michigan. Utilizing state of the art science and technology, Graminex offers the highest quality botanical products available in the marketplace.

Graminex has several facilities and experienced personnel to develop a variety of botanical products, including powdered, standardized extracts, and simple drug ratio extracts. Graminex has more than 10,000 acres available for medicinal plants. There are few companies in the world that can have, under strict supervision, the total cycle of the medicinal plant process. Graminex starts with certified seed, uses no herbicide or pesticides, and finishes with special patented harvester equipment. Final processing is completed in our ISO Q9001-2000 and G.M.P. certified facility.

Because Graminex is a contract manufacturer, equipment to perform a multitude of functions has been developed. Our diverse equipment permits modifying the operating conditions of the manufacturing process to meet customer demand. The new manufacturing plant in Deshler, Ohio consists of 75,000 square feet of manufacturing and 250,000 cubic feet of warehousing. Graminex recently completed a new 60,000 square foot facility at the Deshler site to better service our customers.

Graminex operates in the bulk botanical market specializing in Graminex ™ Flower Pollen Extract, Fabales™ Red Clover Extract and granulated Alfalfa, providing supplement manufacturers with bulk raw materials, standardized extracts and service. Graminex strives to provide its customers with the best quality at the most competitive price. Botanical pharmaceutical products include natural compounds used in various drug development and commercial applications.

Manufacturing

Graminex's products are manufactured to stringent GMP guidelines. Graminex's GMP experience includes manufacturing products for the pharmaceutical and dietary supplement industries. Graminex specializes in Graminex ™ Flower Pollen Extract, Fabales™ Red Clover Extract holding 18% isoflavones and granulated Alfalfa. To assure that the marker compound concentration in the product meets Graminex's specifications, Graminex monitors the stability of each

product in a pharmaceutical quality program. Graminex strives to deliver the highest level of customer satisfaction by assisting in the implementation of analytical methods and by the customization of products to fulfill the customers' requirements and expectations. Graminex has developed numerous proprietary-manufacturing technologies to process raw materials and produce specialized botanical products.

Graminex's expertise in analyzing, identifying, and measuring low concentration compounds (occurring in starting materials), is vital to raw material analysis, process development and quality control. Graminex designs particular applications for manufacturing. This involves selecting the most appropriate growing, harvesting, and processing steps, determining the proper sequence, establishing optimum temperature, pressure, solvent and other parameters. Graminex develops variations of its processes based on the nature of the raw materials used and the specifications of the desired product. Because Graminex is a custom botanical and pharmaceutical manufacturer, Graminex is not only inspected by the applicable regulatory agencies, but by the customers themselves. Graminex's customers come from many different enforcement districts of the Health Authorities, which gives Graminex an overall picture of GMP trends and changes in GMP technology around the world.

Products

Graminex is dedicated to strict GMP compliance in product manufacturing. All products such as our Graminex ™ Flower Pollen Extract, Fabales™ Red Clover Extract and granulated Alfalfa are manufactured under pharmaceutical standards. A continuing employee-training program, equipment/process validation, a Drug Master File and a self-inspection program are part of Graminex's product quality assurance. Validations are designed to qualify new equipment and to evaluate/re-qualify existing equipment that has been modified. Plant inspection, environmental monitoring, action reviews, production record format review and approval of all Standard Operating Procedures are QA functions, which assure production standards. Documentation for Graminex ™ Flower Pollen Extract, Fabales™ Red Clover, granulated Alfalfa and other products can be supplied including in some cases DMF's.

Remember- Graminex has the capability to produce and develop all types of botanical products, including powdered, standardized extracts and simple drug ratio extracts. Total flexibility and the ability to customize products to meet your company's unique requirements is how Graminex operates and delivers.

Most of our products are kept in our warehouse, ready to be shipped. Call us and we will ship your order to you. There are few companies in the world that can have this kind of pharmaceutical plant process cycle under such strict supervision.

Graminex provides botanical products with the degree of superiority you expect and deserve. All of these factors will lead Graminex to become "Your Botanical Source" ™.

Our Development Department

Graminex manufactures natural prescription drugs for foreign markets. With support from experienced pharmaceutical management and scientists at its corporate partners, Graminex also has the capability to file IND's for botanical products.

Development, Formulation, Quality Control and Production Departments, work closely together to design techniques modifying equipment to eliminate problems. The result is a better quality product, minimal manufacturing problems and higher and consistent product yield for our customers.

Complete Quality Control Testing and Batch Documentation

Tests currently performed include:

Some of the Microbiological Testing and Services Include:

Our Mission Statement:

Graminex L.L.C. will supply the highest quality botanicals on time to the exact specifications of each and every customer.

Since its beginning, Graminex has been involved in the development and manufacture of a wide variety of botanical products including Flower Pollen Extract, Fabales™ Red Clover Extract and granulated Alfalfa. Graminex has become the most experienced custom manufacturer of botanical products in the U.S. With the new manufacturing plant in Ohio, Graminex has become one of the largest botanical companies in the U.S. We have a history of excellence with numerous well-known satisfied customers. Many of our customers have

returned to Graminex for other products in addition to their original requirements.

Facility