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Treatment of Outflow Tract Obstruction Due To Benign Prostatic Hyperplasia with the Pollen Extract, Cernilton ® - A Double-Blind, Placebo-Controlled Study
A. C. Buck, R. W. M. Rees, L. Ebeling, A. John
From numerous experimental studies in animals and clinical studies in man there is unequivocal evidence for the role of androgens in the development of benign prostatic hyperplasia, but the precise hormonal interactions which initiate or, indeed, sustain these changes in the prostate gland are unknown (Wilson, 1980; Habib et al., 1981; Stone et al., 1986). The symptoms that ensue from BPH are variable and bear little relation to the size of the gland. They can be either obstructive or functional and irritative, owing to concomitant detrusor instability and alpha-adrenergic overactivity of the sympathetic innervation of the bladder neck and prostatic musculature. The medical approach to the treatment of symptomatic BPH has been both endocrine and neuropharmacological. Read the Full Study
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